Farmacoterapia para tabagismo gestante: Pode?

Pharmacotherapy for smoking cessation during pregnancy

Pregnant women are strongly encouraged to stop smoking, but the efficacy of pharmacotherapy for smoking cessation during pregnancy has been debated. In a prospective questionnaire study of over 1200 pregnant smokers, use of either nicotine replacement therapy (NRT) or bupropion in the first trimester of pregnancy was associated with smoking cessation rates of approximately 80 percent compared with a 0 percent cessation rate for smokers not using either medication [10]. Over 60 percent of NRT and bupropion users who discontinued the medication did not resume smoking during or up to one year after pregnancy. In adjusted analysis, both medications reduced the risk of prematurity and NRT was also associated with a nearly 40 percent reduced risk for small-for-gestational-age infants compared with continued smoking, although the sample sizes were small. We offer pharmacotherapy to pregnant women as we believe the benefits of quitting with pharmacotherapy outweigh the potential risks.

See  'Cigarette smoking: Impact on pregnancy and the neonate', section on 'Nicotine replacement'.

10. Bérard A, Zhao JP, Sheehy O. Success of smoking cessation interventions during pregnancy. Am J Obstet Gynecol 2016.